DIGOXINEMIA

Se discute el uso ele la cligoxina como adyuvante en la terapia cardíaca; se hace referencia a su mecanismo ele acció n y a los diferentes factores fisiológicos y medicamentos que afectan su biodisponibilidad, así como a algunos ele los factores que pueden alterar su cuantificación en líquidos corporales. Se ofrecen recomendaciones para optimizar este determinación y se revisan los niveles terapéuticos recomendados.

The use of digoxin as an adyuvant in cardiac therapy is discussed. Reference is also made to it mechanism of action and to the different physiological and drug induced mechanisms that could affect its bioavailability and absorption. Factors interfering with its quantification in body fluids are also discussed and recommendations are issued in order to optimize the use of this measurement. Recommended therapeutic levels are also revised.